Chronic Obstructive Pulmonary Diseases:Journal of the COPD Foundation

Articles in Press

Peer-reviewed, accepted articles are posted in Articles in Press shortly after editorial acceptance. These posted articles (below) have completed a rigorous peer review process but the articles have NOT been copyedited or designed. Copyedited, designed, final versions of these articles will be created and published in a Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation (JCOPDF) upcoming issue. Articles in Press citations/abstracts are submitted to PubMed.

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Use of the Evaluating Respiratory Symptoms™ in COPD as an Outcome Measure in Clinical Trials: A Rapid Systematic Review

Donald M. Bushnell1, Rozanne Wilson1, Florian S. Gutzwiller2, Nancy K. Leidy1, Carolina Hache2, Chau Thach2, Claus F. Vogelmeier3

Citation: Bushnell DM, Wilson R, Gutziller FS, et al. Use of the Evaluating Respiratory Symptoms™ in COPD as an outcome measure in clinical trials: a rapid systematic review. Chronic Obstr Pulm Dis. 2021; Published online October 1, 2021. doi:

Outcomes of Patients with COPD Hospitalized for Coronavirus Disease 2019

Daniel A. Puebla Neira, MD1 Abigail Watts, MD 1 Justin Seashore, MD1 Alexander Duarte, MD1 Shawn P. Nishi, MD1 Efstathia Polychronopoulou, MS, MPH2 Yong-Fang Kuo, PhD2-3 Jacques Baillargeon, PhD3 Gulshan Sharma, MD, MPH1,3

Citation: Puebla Neira DA, Watts A, Seashore J, et al. Outcomes of patients with COPD hospitalized for coronavirus disease 2019. Chronic Obstr Pulm Dis. 2021; Published online October 1, 2021. doi:

Increased Health Care Resource Utilization and Costs Associated with Herpes Zoster Among Patients Aged ≥50 Years with Chronic Obstructive Pulmonary Disease in the United States

Parinaz Ghaswalla, PhD,1 Philippe Thompson-Leduc, MSc,2 Wendy Y. Cheng, PhD, MPH,3 Colin Kunzweiler, PhD, MS,3 Min-Jung Wang, ScD,3 Michael Bogart, PharmD,4 Brandon J. Patterson, PharmD, PhD,1,* Mei Sheng Duh, ScD, MPH,3 John Wojciehowski, BA,3 Suna Park, MSc,3 Barbara P. Yawn, MD, MSc5

Citation: Ghaswalla P, Thompson-Leduc P, Cheng WY, et al. Increased health care resource utilization and costs associated with herpes zoster among patients aged ≥50 years with chronic obstructive pulmonary disease in the United States. Chronic Obstr Pulm Dis. 2021; Published online October 1, 2021. doi:

Decrease in Exacerbations During the Coronavirus Disease 2019 Pandemic in a Cohort of Veterans with COPD

Christian Trujillo, MD1 Brian Garnet, MD2,3 Ali Vaeli Zadeh, MD2 Gisel Urdaneta, MD2 Michael Campos, MD2,3

Citation: Trujillo C, Garnet B, Zadeh AV, Urdaneta G, Campos M. Decrease in exacerbations during the coronavirus disease 2019 pandemic in a cohort of veterans with COPD. Chronic Obstr Pulm Dis. 2021; Published online September 16, 2021. doi:

Pilot Study of a Patient Experience with an ELLIPTA Inhaler Electronic Medication Monitor and Associated Integrated System: A Prospective Observational Study Using the COPD Patient-Powered Research Network

Barbara P. Yawn, MD, MSc1*,2 Gretchen M. McCreary, MA1 John A. Linnell, BA1 Cara B. Pasquale, MPH1 Elisha Malanga, BS1 Radmila Choate, PhD, MPH1,3 David A. Stempel, MD4* Rahul Gondalia, PhD, MPH5* Leanne Kaye, PhD, MPH5* Kathryn A. Collison, MPH, PMP4* Benjamin S. Wu, PharmD, MS4* Daniel Gratie, PharmD4* Richard H. Stanford, PharmD, MS4* Ryan Tomlinson, MRPharmS, PhD6

Citation: Yawn BP, McCreary GM, Linnell JA, et al. Pilot study of a patient experience with an ELLIPTA inhaler electronic medication monitor and associated integrated system: a prospective observational study using the COPD Patient-Powered Research Network. Chronic Obstr Pulm Dis. 2021; Published online September 10, 2021. doi:

Self-reported COPD Medication Use and Adherence in the COPD Foundation Patient- Powered Registry Network

Cara B. Pasquale, MPH1 Radmila Choate, PhD, MPH,1,2 Gretchen McCreary, MA1 Richard A Mularski, MD, MSHS, MCR, ATSF, FCCP, FACP3,4,5 William Clark1 MaryEllen Houlihan1 Elisha Malanga, BS1 Barbara P. Yawn, MD, MSc, MSPH, FAAFP1,6

Citation: Pasquale CB, Choate R, McCreary G, et al. Self-reported COPD medication use and adherence in the COPD Foundation patient-powered registry network. Chronic Obstr Pulm Dis. 2021; Published online September 8, 2021. doi:

Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity

Heleen Demeyer1,2, Divya Mohan3, Chris Burtin4, Anouk Vaes5, Matthew Heasley6, Russell Bowler7, Richard Casaburi8, Christopher B Cooper9, Solange Corriol-Rohou10, Anja Frei11, Alan Hamilton12, Nicholas S. Hopkinson13,14, Niklas Karlsson15, William D-C. Man13,16, Marilyn L. Moy17,18, Fabio Pitta19, Michael I. Polkey13,14, Milo Puhan11, Stephen I. Rennard20, Carolyn L. Rochester21,22, Harry B. Rossiter8,23, Frank Sciurba24, Sally Singh25, Ruth Tal-Singer26, Ioannis Vogiatzis27, Henrik Watz28, Rob Van Lummel29, Jeremy Wyatt30, Debora D. Merrill26, Martijn A Spruit4,5,31, Judith Garcia-Aymerich32,33,34, Thierry Troosters1; On behalf of the COPD Biomarker Qualification Consortium (CBQC) Task Force on Physical Activity

Citation: Demeyer H, Mohan D, Burtin C, et al. Objectively measured physical activity in patients with COPD: recommendations from an international task force on physical activity. Chronic Obstr Pulm Dis. 2021; Published online August 25, 2021. doi:

Intra-Individual Variability in Serum Alpha-1 Antitrypsin Levels

Annie Haillot, MD1*, Andrée-Anne Pelland, MD1*, Yohan Bossé, PhD1, Tomás P. Carroll, PhD2,3, François Maltais, MD1, Ronald J. Dandurand, MD4,5,6,7,8

Citation: Haillot A, Pelland A-A, Bosse Y, et al. Intra-individual variability in serum alpha-1 antitrypsin levels. Chronic Obstr Pulm Dis. 2021; Published online August 17, 2021. doi:

Comparative Effectiveness of Roflumilast and Azithromycin for the Treatment of Chronic Obstructive Pulmonary Disease

Jenny Lam, MD, PhD1,2 Ivy Tonnu-Mihara3 Nicholas J Kenyon, MD, MAS4,5 Brooks T Kuhn, MD, MAS4,5

Citation: Lam J, Tonnu-Mihara I, Kenyon NJ, Kuhn BT. Comparative effectiveness of roflumilast and azithromycin for the treatment of chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2021; Published online August 11, 2021. doi:

Losartan Effects on Emphysema Progression Randomized Clinical Trial: Rationale, Design, Recruitment, and Retention

Robert A. Wise1 Janet T. Holbrook2 Robert H. Brown1 Gerard J. Criner,3 Mark T. Dransfield4 MeiLan K. Han5 Jerry A. Krishnan6 Ellen Looney,7 Enid Neptune1 Vicky Palombizio8 Alexis Rea2

Citation: American Lung Association Airways Clinical Research Centers. Wise R, Holbrook JT, Brown RH, et al. Losartan effects on emphysema progression randomized clinical trial: rationale, design, recruitment, and retention. Chronic Obstr Pulm Dis. 2021; Published online August 2, 2021. doi:

Cytomegalovirus Seropositivity is Associated with Airflow Limitation in a Cohort of Veterans with a High Prevalence of Smoking

Robert Burkes, MD, MSCR1,2 Andrew Osterburg, PhD1 Timothy Hwalek, DO1 Laura Lach2 Ralph J. Panos, MD1,2 Michael T. Borchers, PhD1,2

Citation: Burkes R, Osterburg A, Hwalek T, Lach L, Panos RJ, Borchers MT. Cytomegalovirus seropositivity is associated with airflow limitation in a cohort of veterans with a high prevalence of smoking. Chronic Obstr Pulm Dis. 2021; Published online July 30, 2021. doi:

Pulmonary Rehabilitation and Readmission Rates for Medicare Beneficiaries with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Laura C. Myers, MD MPH1 Mohammad Kamal Faridi, MPH2 Kohei Hasegawa, MD, MPH2 Carlos A. Camargo Jr., MD, DrPH2

Citation: Myers LC, Faridi MK, Hasegawa K, Camargo CA. Pulmonary rehabilitation and readmission rates for Medicare beneficiaries with acute exacerbation of chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2021; Published online July 16, 2021. doi: