Chronic Obstructive Pulmonary Diseases:Journal of the COPD Foundation

Articles in Press

Peer-reviewed, accepted articles are posted in Articles in Press shortly after editorial acceptance. These posted articles (below) have completed a rigorous peer review process but the articles have NOT been copyedited or designed. Copyedited, designed, final versions of these articles will be created and published in a Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation (JCOPDF) upcoming issue. Articles in Press citations/abstracts are submitted to PubMed.

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Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS

Robert M. Burkes, MD, MSCR1 David J. Couper, PhD2 Igor Z. Barjaktarevic, MD, PhD3 Christopher B. Cooper, MD4 Wassim W. Labaki, MD5 Meilan K. Han, MD5 Prescott G. Woodruff MD, MPH6 Stephen C. Lazarus, MD6 Trisha M. Parek,h DO7 Robert Paine, III, MD8 Alejandro P. Comellas, MD9 Russell P. Bowler, MD, PhD10 Laura R. Loehr, MD, PhD11 Nirupama Putcha, MD, MHS12 Robert A. Wise, MD12 Todd T. Brown, MD, PhD13 M. Bradley Drummond, MD, MHS1

Citation: Burkes RM, Couper DJ, Barjaktarevic IZ, et al. Age-dependent associations between 25-hydroxy vitamin D levels and COPD symptoms: analysis of SPIROMICS. Chronic Obstr Pulm Dis. 2021; Published online April 6, 2021. doi:

Development of Respercise® a Digital Application for Standardizing Home Exercise in COPD Clinical Trials

John G Yonchuk M.S. 1, Divya Mohan M.D. Ph.D. 2*, Nathan K LeBrasseur M.S. Ph.D.3, Ashley R George Ph.D.4*, Sally Singh Ph.D. 5, Ruth Tal-Singer Ph.D.6*

Citation: Yonchuk JG, Mohan D, LeBrasseur NK, George AR , Singh S, Tal-Singer R. Development of Respercise® a digital application for standardizing home exercise in COPD clinical trials. Chronic Obstr Pulm Dis. 2021; Published online March 26, 2021. doi:

Impact of Chronic Obstructive Pulmonary Disease and Emphysema on Outcomes of Hospitalized Patients with COVID-19 Pneumonia

Robert M Marron, MD1, Matthew Zheng, MD1, Gustavo Fernandez Romero, MD1, Huaqing Zhao, PhD2, Raj Patel, MD3, Ian Leopold, MD3, Ashanth Thomas, MD3, Taylor Standiford, MD3, Maruti Kumaran, MD3, Nicole Patlakh Jeffrey Stewart, MD1, Gerard J Criner, MD1 and the Temple University COVID-19 Research Group

Citation: Marron RM, Zheng M, Romero GF, et al. Impact of chronic obstructive pulmonary disease and emphysema on outcomes of hospitalized patients with COVID-19 pneumonia. Chronic Obstr Pulm Dis. 2021; Published online March 26, 2021. doi:

Symptom Burden and Medication Use Among Patients With Nontuberculous Mycobacterial Lung Disease

Vira Pravosud1 David M. Mannino1,2 Delia Prieto2 Quanwu Zhang3 Radmila Choate1,2 Elisha Malanga2 Timothy R. Aksamit4

Citation: Pravosud V, Mannino DM, Prieto D, Zhang Q, Choate R, Malanga E, Aksamit TR. Symptom burden and medication use among patients with nontuberculous mycobacterial lung disease. Chronic Obstr Pulm Dis. 2021; Published online February 19, 2021. doi:

Does Evaluation and Management of COPD Follow Therapeutic Strategy Recommendations?

Fernando J. Martinez, MD, MS1 Byron Thomashow, MD2 Tamar Sapir, PhD3 Laura Simone, PhD3 Jeffrey Carter, PhD3 MeiLan Han, MD, MS4

Citation: Martinez FJ, Thomashow B, Sapir T, Simone L, Carter J, Han M. Does evaluation and management of COPD follow therapeutic strategy recommendations? Chronic Obstr Pulm Dis. 2021; Published online February 19, 2021. doi:

Effect of Triple Therapy with Budesonide-Formoterol-Tiotropium Versus Placebo-Tiotropium on Sleep Quality in Patients with Chronic Obstructive Pulmonary Disease

Samuel L Krachman, DO1 Maria Elena Vega, MD1 Daohai Yu, PhD2 Joseph Demidovich, DO1 Harsh Patel, MD1 Frederic Jaffe, DO1 Xavi Soler, MD3 Tasheen Shariff, RPSGT1 Gilbert E D'Alonzo, DO1 Wissam Chatila, MD1 Sheila Weaver, DO1 Yasmin Daraz1* Sydney Cohen1* Gerard J Criner, MD1

Citation: Krachman SL, Vega ME, Yu D, et al. Effect of triple therapy with budesonide-formoterol-tiotropium versus placebo-tiotropium on sleep quality in patients with chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2021; Published online February 5, 2021. doi:

New Adopters of Telemedicine During the Coronavirus-19 Pandemic in Respondents to an Online Community Survey: The Case for Access to Remote Management Tools for Individuals with Chronic Obstructive Pulmonary Disease

Danielle M. Boyce, MPH1 Byron M. Thomashow, MD1,2 Jamie Sullivan, MPH1 Ruth Tal-Singer, PhD1

Citation: Boyce DM, Thomashow BM, Sullivan J, Tal-Singer R. New adopters of telemedicine during the coronavirus-19 pandemic in respondents to an online community survey: the case for access to remote management tools for individuals with chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2020; Published online December 8, 2020. doi:

Progression of Emphysema and Small Airways Disease in Cigarette Smokers

Esther Pompe1 Camille M. Moore2 Firdaus A.A. Mohamed Hoesein3 Pim A. de Jong3 Jean-Paul Charbonnier4 MeiLan K. Han5 Steven M. Humphries6 Charles R. Hatt7 Craig J. Galbán8,9 Ed K. Silverman10,11 James D. Crapo12 George R. Washko11 Elisabeth A. Regan13 Barry Make12 Matthew Strand2 Jan-Willem J. Lammers1 Eva M. van Rikxoort4 David A. Lynch6 on behalf of the COPDGene investigators

Citation: Pompe E, Moore CM, Hoesein FAAM, et al for the COPDGene Investigators. Progression of emphysema and small airways disease in cigarette smokers. Chronic Obstr Pulm Dis. 2020; Published online December 2, 2020. doi:

Improving Screening for Alpha-1 Antitrypsin Deficiency With Direct Testing in the Pulmonary Function Testing Laboratory

Samuel Gurevich, MD1,2 Andrew Daya, MD2 Cristiana Da Silva, RRT, BS2 Christine Girard, MD2 Franck Rahaghi, MD2

Citation: Gurevich S, Daya A, Da Silva C, Girard C, Rahaghi F. Improving screening for alpha-1 antitrypsin with direct testing in the pulmonary function testing laboratory. Chronic Obstr Pulm Dis. 2020; Published online December 2, 2020. doi: