Chronic Obstructive Pulmonary Diseases:Journal of the COPD Foundation

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Original Rersearch | This corrects the article, “Clinical Implications of Pseudomonas Aeruginosa Colonization in Chronic Obstructive Pulmonary Disease Patients,” published in Volume 12, Issue 2, pp. 137-145.

Erratum

Wang Chun Kwok, MBBS1 Terence Chi Chun Tam, MBBS1 Chi Hung Chau, MBBS2 Fai Man Lam, MBBS2 James Chung Man Ho, MD1

Author Affiliations

  1. Division of Respiratory Medicine, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
  2. Tuberculosis and Chest Unit, Grantham Hospital, Aberdeen, Hong Kong Special Administrative Region, China

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Abstract

Background:Pseudomonas aeruginosa is an important pathogen in patients with chronic respiratory diseases. It can colonize the airways and could have prognostic value in bronchiectasis and cystic fibrosis. Its role in chronic obstructive pulmonary disease (COPD) is less well-defined.

Methods: A prospective study was conducted in Hong Kong to investigate the possible association between Pseudomonas aeruginosa colonization and acute exacerbation of COPD (AECOPD) risks.

Results: Among 327 Chinese patients with COPD, 33 (10.1%) of the patients had Pseudomonas aeruginosa colonization. Patients with or without Pseudomonas aeruginosa colonization had similar background characteristics. Patients with Pseudomonas aeruginosa colonization had increased risks of moderate to severe AECOPD, severe AECOPD, and pneumonia with an adjusted odds ratio (aOR) of 3.15 (95% CI 1.05−9.48, p=0.042), 2.59 (95% CI 1.01₋6.64, p=0.048), and 4.19 (95% CI 1.40₋12.54, p=0.011) respectively. Patients with Pseudomonas aeruginosa colonization also had increased annual frequency of moderate to severe AECOPDs, median 0 (0₋0.93) in the non-Pseudomonas aeruginosa colonization group and 1.35 (0₋3.39) in the Pseudomonas aeruginosa colonization group, with a p-value of 0.005 in multivariate linear regression.

Conclusion: Pseudomonas aeruginosa colonization is a potential independent risk factor for moderate to severe AECOPD and pneumonia among patients with COPD without coexisting bronchiectasis.

Citation

Citation: Erratum. Chronic Obstr Pulm Dis. 2025; 12(3): 1-1. doi: http://doi.org/10.15326/jcopdf.2024.0582E

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Running Head: Pseudomonas Aeruginosa Colonization in COPD Patients

Citation: Erratum. Chronic Obstr Pulm Dis. 2025; 12(3): 1-1. doi: http://doi.org/10.15326/jcopdf.2024.0582E

In Volume 12, Issue 2 (March 2025), the article “Clinical Implications of Pseudomonas Aeruginosa Colonization in Chronic Obstructive Pulmonary Disease Patients” by Kwok et al contained an error in the Results: Mortality section. The second sentence of this section should have read:

“There was no statistical difference in the mortality risks in the 2 groups, with a hazard ratio of 1.06 (95% CI=0.48–2.32, p=0.89) for the Pseudomonas aeruginosa colonization group.”

The authors regret this error.

This correction has been made to the online and PDF versions of the article. http://doi.org/10.15326/jcopdf.2024.0582

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