Katherine Hickman, MBBS; Yasir Tarabichi, MD, MSCR; Andrew P. Dickens, MSc,PhD; Rachel Pullen, MBChB; Margee Kerr, PhD; Amy Couper, BSc; Alexander Evans, MSc; James Gatenby, MD; Luis Alves, MD; Cono Ariti, MSc; Mona Bafadhel, MBChB, MRCP, PhD; Victoria Carter, BSc; James Chalmers, MBChB, PhD; Rongchang Chen, MD; Graham Devereux, MBChB, PhD, FRCP; M. Bradley Drummond, MD, MHS; J. Martin Gibson, MD, FRCP; David M. G. Halpin, MD, DPhil; MeiLan K. Han, MD, MS; Nicola A. Hanania, MD, MS; John R. Hurst, PhD; Alan Kaplan, MD; Konstantinos Kostikas, MD, PhD, FERS; Barry Make, MD; Douglas Mapel, MD, MPH; Jonathan Marshall, BSc, PhD; Fernando Martinez, MD, MS; Catherine Meldrum, PhD, RN; Marije van Melle, PhD; Marc Miravitlles, MD; Tamsin Morris, BSc; Hana Mullerova, PhD; Ruth Murray, PhD; Shigeo Muro, MD, PhD; Clementine Nordon, MD, PhD; Jill Ohar, MD; Wilson Pace, MD, FAAFP; Michael Pollack, MSc; Jennifer K. Quint, FRCP; Anita Sharma, FRACGP, MBBS; Dave Singh, MD; Mukesh Singh, MBBS; Frank Trudo, MD, MBA; Dennis Williams, PharmD; Tom Wilkinson, MA Cantab, MBBS, PhD, FRCP, FERS; Tonya Winders, MBA; David Price, MA, MBBC, FRCGP
Chronic obstructive pulmonary disease (COPD) is a long-term lung condition. People with COPD may experience flare-ups in which their symptoms, like coughing and shortness of breath, worsen. People who experience frequent flare-ups have a higher risk of poor health results. Treatments are available, but many do not receive them, and many who have frequent flare-ups have not been screened for COPD. Identifying people with a higher risk for these flare-ups and changing their treatment could improve their long-term health.
This article describes the U.S. and U.K. PREVAIL studies evaluating a program to improve the care of patients with COPD called CONQUEST. The CONQUEST program starts with identifying patients in primary care practices who have frequent flare-ups and may benefit from having their COPD symptoms evaluated and changes made to their treatment. Patients are then invited to meet with health care professionals for a clinical review and to consider treatment options according to the clinical guidance and support offered as part of CONQUEST.
The PREVAIL studies will then compare results over an average of 2 years among those who participated in CONQUEST and those who did not. If the program is beneficial, it could be used by others to improve the long-term health of this higher-risk population.